SRC is committed to supporting the chemical hazard and risk assessment needs of government and commercial organizations responsible for the evaluation of occupational and environmental hazards. For more than 20 years, SRC has provided data collection and evaluation services in the environmental sciences to:

• U.S. Environmental Protection Agency
   
• National Library of Medicine
   
• Occupational Safety and Health Administration
   
• Agency for Toxic Substances and Disease Registry
   
• Department of Defense

SRC has prepared over 4,000 technical reviews on hundreds of chemicals and chemical classes, making SRC one of the most experienced, non-government, not-for-profit specialists in chemical hazard assessment. Technical strengths of SRC in health and environmental sciences include:

• Development and application of advanced concepts in quantitative exposure and risk assessment for single chemicals and mixtures
   
• Critical review and analysis of toxicological and environmental literature
   
• Development of environmental and toxicological data bases

Health and Environmental Assessments
SRC scientists perform hazard evaluations, exposure assessments, dose-response analyses, and risk characterizations of single chemicals and chemical mixtures. SRC has prepared assessments on several thousand chemicals, including hundreds of assessments to assist EPA in deriving inhalation Reference Concentrations, Oral Reference doses and cancer potency values. SRC assists EPA in conducting and reviewing site risk characterizations for Superfund.

Risk Assessment Research
SRC scientists participate in the latest developments in risk assessment methodology and develop new approaches to complex assessments. SRC assisted EPA in developing guidelines for assessing risks associated with exposure to chemical mixtures and risks associated with direct and indirect exposures to municipal waste combustor emissions and other stationary sources. SRC's research program currently includes projects that span most of the current issues confronting risk assessors, including problems in single chemical assessment, modeling complex mixtures, multimedia exposures, comparative risk and pollution prevention models.

Lead Archive (pdf)
A bibliography of technical reports on lead toxicology and risk assessment.

SRC scientists staff a hotline for EPA called the IEUBK Technical Support Center. IEUBK is the Integrated Exposure Uptake Biokinetic Model for lead in children. The SRC scientists address lead contamination concerns from regulators, industry and the public.  

Metals Bibliography (pdf)
A bibliography of technical reports on the toxicology of metals (this will be available soon).

Bioavailability Data on Metals
Evaluated data relevant to estimating the bioavailability of metals in humans

• Cadmium Bioavailability
   
• Cadmium Bioavailability in Food and Water
   
• Lead Bioavailability

ISE Model Software
The Integrated Stochastic Exposure (ISE) Model is a probabilistic exposure model developed by SRC for use in childhood lead risk assessments. ISE uses the same exposure, uptake, and biokinetic variables as the U.S. EPA IEUBK Model for Lead in Children.

Research Publications
See our Research Publications section for a selected list of our recent publications organized by category and chronologically.

Special Topics and Chemical Classes
SRC has prepared over 50 monographs/profiles for process industries that produce or consume chemicals, or have other health concerns (e.g. noise, fibers, etc.). These are listed under Special Topics. For 30 years SRC has developed numerous chemical monographs/profiles sponsored by industry and government that have included tens of thousands of chemicals. Many of these are listed under Chemical Classes.

Recent Reports and Presentations
See our Reports & Presentations section for presentations which can be viewed and reports which can be downloaded. Most of SRC's recent presentations at the annual meetings of the Society of Toxicology are available here.